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With the latest technological advancements at their fingertips, they're setting new benchmarks in personalized body contouring. Learn more about Anti-aging injections New Westminster here At Manhas Health Co., you're more than just a client; you're part of a community where each individual's unique journey to confidence and health is celebrated. Learn more about Manhas Health Co. here. Our team uses this information to craft a tailored plan that aligns with your vision and ensures the outcomes you're aiming for. Our approach ensures that each procedure, from minimally invasive treatments to more extensive interventions, is chosen and adjusted specifically for you.
The treatment rooms boast the latest in aesthetic technology, ensuring that you're getting the most advanced treatments available. Botox for skin rejuvenation You'll also be given instructions on how to maintain hygiene in the treated area. Results will gradually appear over the next few weeks, with optimal outcomes visible after a series of treatments.
At Manhas Health Co, we're committed to making your beauty goals a reality. The system utilizes cutting-edge, non-invasive methods to ensure you're not only getting effective results but are also experiencing a process that's as painless as possible. Love handles, belly fat, and thigh areas show remarkable improvement, looking firmer and more toned.
Firstly, avoid direct sun exposure for at least a week before your appointment. Moreover, Evolve-X offers versatility that's unmatched by many alternatives. It's designed to target and remodel larger areas with precision, without the need for incisions or anesthesia.

You'll feel a warm sensation as the device glides over your skin, but it's generally painless, thanks to the precise temperature control. This innovative technology reshapes your body by targeting fat and enhancing muscle tone without incisions, anesthesia, or downtime. Inspired by the transformative experiences shared by clients, it's now your opportunity to explore how vaginal rejuvenation at Manhas Health Co. can benefit you by scheduling your consultation. Aesthetic clinic These growth factors signal your skin cells and hair follicles to function optimally, increasing blood supply to the follicles and expanding the hair shaft.
These usually resolve within a few days. Exploring the benefits of treatment, you'll discover that rejuvenation can significantly enhance your quality of life by boosting confidence and comfort in your intimate health. If you'd prefer, you can also reach out directly by calling our office. Botox for men
Moreover, Botox can alleviate chronic migraines by relaxing muscles that contribute to tension and pain. It's a non-invasive procedure, meaning you won't have to worry about any downtime. Read more about Anti-aging injections New Westminster here You can expect to return to your daily activities shortly after the session ends.
Lastly, consider integrating antioxidants into your skincare lineup. Your skin is as individual as you are, and it deserves a regimen that reflects that. When you arrive for your first appointment, you'll be greeted warmly by our team.

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The area now known as New Westminster was originally inhabited by Kwantlen First Nation The discovery of gold in BC and the arrival of gold seekers from the south prompted fear amongst the settlers that Americans may invade to take over this land.

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Nearby Tourist Attractions

Mundy Park

Tourist attraction, City park
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178 acres of forest habitat with 2 lakes, sports facilities, disc golf & an outdoor pool.

Port Moody Station Museum

Tourist attraction, Entertainer, Historical landmark, History museum, Local history museum
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Waterfront recreation area with a pier, pool, skate park, restaurant, playground & boat ramp.

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Tourist attraction, City park, Hiking area
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This walking trail along the Burrard Inlet offers sweeping views & allows leashed dogs.

Burnaby Fraser Foreshore Park

Tourist attraction, Park
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Whalley
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World Police and Fire Games decoration

Metrotown
Tourist attraction
World Police and Fire Games decoration, 3789 BC-99A, Burnaby, BC V5H 1Y4

Citations and other links

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At Manhas Health Co., you'll find a supportive environment where you can openly discuss your concerns and goals. Your practitioner will work closely with you, utilizing Evolve-X's capabilities to design a program that addresses your concerns, whether it's your abdomen, thighs, arms, or any area in need of enhancement. At Manhas Health Co, we're dedicated to helping you look and feel your best, with a personalized touch every step of the way. We prioritize safety and results, employing state-of-the-art technology and personalized protocols that align with your aesthetic goals.

What sets Advanced Forma apart is its ability to provide cumulative results. Moreover, the cumulative effect of regular sessions can lead to long-term improvements, ensuring that your skin not only looks better now but continues to improve. A friendly staff member will assist you in finding a suitable time and answer any questions you might've about the services or the clinic itself.

It's also incredibly versatile, catering to a range of skin concerns beyond aging, such as sagging skin and undefined facial contours. You won't see the full effects immediately. You're tapping into a world of aesthetic and therapeutic advantages that can transform your appearance and well-being.

You might wonder how it works. Botox beauty trends We believe in fostering long-term relationships with our clients, guiding you through your aesthetic journey with empathy and expertise. Botox for marionette lines We're committed to offering you a suite of services that cater to long-term beauty and wellness.

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At Manhas Health Co., we're committed to providing you with the most effective and comfortable experience. Their arsenal includes non-invasive treatments that require minimal to no downtime, meaning you can get back to your daily routine almost immediately. By injecting your scalp with a concentration of your own platelets, it stimulates hair follicles to grow. After payment, you're all set! Their team of experts uses state-of-the-art technology to ensure that you're receiving the most effective treatments available.

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At Manhas Health, our experts bring a wealth of knowledge to your Evolve-X body sculpting journey, ensuring you're in the best hands for achieving your desired results. To ensure your safety, it's essential to follow all pre and post-treatment instructions provided by your specialist. Their team of skilled professionals is constantly updating their knowledge and skills to ensure you receive the best possible care. And if safety concerns have kept you at bay, the following insights into the procedure's safety profile and the care required post-treatment might just change your mind.

These side effects typically resolve within a few hours to days. Delving into the science behind sculpting, it's crucial to understand how radiofrequency technology precisely targets the deeper layers of your skin to promote collagen production. Botox, often heralded for its ability to reduce wrinkles, offers a multitude of benefits that go beyond mere cosmetic enhancements. Advanced Botox techniques By choosing Morpheus 8, you're opting for a non-surgical way to achieve significant, long-lasting improvements in your skin's appearance.

Transitioning from Botox, you'll find that fillers offer another transformative path to rejuvenation and beauty at Manhas Health Co. From laser skin rejuvenation to non-invasive body contouring, our technologies are designed to offer effective results with minimal discomfort and downtime. Lastly, the results speak for themselves – they're designed to be natural-looking and long-lasting. Botox for bunny lines An in-depth consultation with a qualified practitioner in Anti-aging injections New Westminster can help determine if Morpheus 8 aligns with your skin goals and medical history.

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The result? You'll find privacy and comfort are prioritized, creating a serene environment that feels like a retreat from the outside world. At Manhas Health Co., we believe in unlocking your natural beauty by enhancing what makes you uniquely you. The science behind this innovation taps into cutting-edge techniques to ensure you're not just seeing temporary improvements but potentially long-lasting results. Why choose Manhas Health Co?

You might wonder if it's right for you. Choosing Evolve-X at Manhas Health Co isn't just about changing how you look; it's about embracing a healthier, more confident you. To kick off your Evolve-X body sculpting journey, the first step is scheduling a consultation with a Manhas Health expert. Having prepared for your treatment at Manhas Health Co, you may now wonder what the actual session involves.

This not only gets rid of dead skin cells but also helps in minimizing the appearance of fine lines, acne scars, and uneven skin tone. You'll find an intuitive online booking system that lets you choose a time and date that best fits your schedule. Post-treatment, the specialist will apply a soothing gel or cream to the treated areas and discuss aftercare instructions to ensure optimal results. This modern approach at Manhas Health Co. targets various concerns, from aesthetic changes to functional improvements, ensuring you feel your best. Skin clinic

Our state-of-the-art laser technology is designed to suit various skin types and tones, ensuring personalized care for every client. These versatile treatments plunge into the world of cosmetic enhancement with the promise of instant volume, smoothing out wrinkles, and sculpting facial contours without the need for invasive surgery. We'll explore the intricacies behind Evolve-X, how it compares to traditional methods, and why it could be the personalized approach you've been searching for. After diligently following post-treatment care tips, you're now ready to celebrate the glowing results of your dermaplaning or chemical peel. Affordable Botox

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After establishing a personalized plan tailored to your needs, it's crucial to highlight the comfort and safety features that set Evolve-X apart. Always disclose your medical history and current medications during your consultation to further safeguard your health. That's why we'll discuss all costs and payment options with you during your initial consultation. Anti-wrinkle clinic Whether you're looking for advanced skin treatments, innovative anti-aging solutions, or body sculpting options, they've got you covered.

Look for board-certified dermatologists or cosmetic surgeons who can demonstrate a track record of successful outcomes. You might experience temporary redness, swelling, or a slight tingling sensation immediately after the treatment. This sample is then spun in a centrifuge to separate the platelet-rich plasma (PRP) from other blood components.

You're probably wondering how it feels and how much time you'll need to commit. This process not only tightens your existing skin but also promotes the growth of new, healthy skin cells. Botox for chin dimpling You'll find each visit to be comfortable and relaxing, with most treatments requiring no downtime.

Dive into the world of non-surgical treatments and see the difference for yourself. These products are less harsh and help retain the natural moisture of your scalp and hair, promoting a healthier growth environment. Botox injection techniques That's why we kick off your body sculpting journey with a comprehensive consultation.

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You'll be amazed at the diversity of treatments available. Each treatment is designed with your safety and comfort in mind, ensuring you receive the best care possible. You can literally have a session and jump back into your daily routine immediately after. Seeing is believing, and in this case, the after results speak volumes about the power of Advanced Forma Face Sculpting to rejuvenate and refresh.
From board-certified dermatologists to skilled aestheticians, we've handpicked the best in the industry to ensure your experience is nothing short of exceptional. If you're looking for something a bit more targeted, radiofrequency treatments might be up your alley. From the moment you step into our clinic in Anti-aging injections New Westminster, you'll find a supportive environment where your concerns and aspirations are heard. Certified Botox professional
It's a smart choice for those seeking effective, non-invasive body sculpting solutions. Certain medications can affect how your skin reacts to the treatment, so it's vital to have an open conversation about your medical history. Choosing Evolve-X at Manhas Health Co means opting for a cutting-edge, pain-free path to the body you've always wanted.
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Facials may include the use of a facial mask.

A facial is a family of skin care treatments for the face, including steam, exfoliation (physical and chemical), extraction, creams, lotions, facial masks, peels, and massage. They are normally performed in beauty salons, but are also a common spa treatment. They are used for general skin health as well as for specific skin conditions. Types of facials include European facial,[1] LED light therapy facials, hydrafacials and mini-facials.

Facial mask

[edit]

There are different kinds of masks (e.g., clay, cactus, cucumber) for different purposes: deep-cleansing, by penetrating the pores; healing acne scars or hyper-pigmentation; brightening, for a gradual illumination of the skin tone. Facial masks also help with anti-aging, acne, crows feet, under eye bags, sagging lids, dark circles, puffiness,[2] and more. Some masks are designed to dry or solidify on the face, almost like plaster; others just remain wet. The green face mask is very essential and benefited.

Masks are removed by either rinsing the face with water, wiping off with a damp cloth, or peeling off of the face. Duration for wearing a mask varies with the type of mask, and manufacturer's usage instructions. The time can range from a few minutes to overnight. Those with sensitive skin are advised to first test out the mask on a small portion of the skin, in order to check for any irritations. Some facial masks are not suited to frequent use. A glycolic mask should not be used more frequently than once a month to avoid the risk of burning the skin.

Masks can be found anywhere from drugstores to department stores and can vary in consistency and form. Setting masks include: clay, which is a thicker consistency, and will draw out impurities (and sometimes, natural oils, too) from the pores; a cream, which stays damp to hydrate the skin; sheet-style, in which a paper mask is dampened with liquid to tone and moisturize the skin; and lastly, a hybrid/clay and cream form that includes small beads for removing dead surface skin cells. Non-setting facial masks include warm oil and paraffin wax masks. These different forms are made to suit different skin types (e.g., oily or dry), and different skincare goals or needs (e.g., moisturizing, cleansing, exfoliating). Clay and mud masks suit oily and some "combination" skin types,[3] while cream-based masks tend to suit dry and sensitive skin types. There are also peel-off masks which are used to remove thin layers of dead skin cells and dirt.[4]

See also

[edit]

References

[edit]
  1. ^ Eastern European Beauty Secrets and Skin Care Techniques. Dorrance Publishing. ISBN 978-1-4349-7452-5.
  2. ^ Bioelements. "Do I need a facial? 32 reasons you absolutely need one". Bioelements. Archived from the original on 2021-05-16. Retrieved 2021-05-16.
  3. ^ Remedios, Faye (2022-07-01). "The do's and don'ts of mud masks, and why it will be your newest skin obsession". Vogue India. Retrieved 2023-01-31.
  4. ^ "What type of face mask is best for my skin type? | Paula's Choice". www.paulaschoice-eu.com. Retrieved 2021-05-16.

Military Policlinic in Legionowo, Poland

A clinic (or outpatient clinic or ambulatory care clinic) is a health facility that is primarily focused on the care of outpatients. Clinics can be privately operated or publicly managed and funded. They typically cover the primary care needs of populations in local communities, in contrast to larger hospitals which offer more specialized treatments and admit inpatients for overnight stays.

Most commonly, the English word clinic refers to a general practice, run by one or more general practitioners offering small therapeutic treatments, but it can also mean a specialist clinic. Some clinics retain the name "clinic" even while growing into institutions as large as major hospitals or becoming associated with a hospital or medical school.

Etymology

[edit]
The entrance to a surgery clinic in Greenwich, London

The word clinic derives from Ancient Greek κλίνειν klinein meaning to slope, lean or recline. Hence κλίνη klinē is a couch or bed and κλινικός klinikos is a physician who visits his patients in their beds.[1] In Latin, this became clīnicus.[2][3]

An early use of the word clinic was "one who receives baptism on a sick bed".[4]

Overview

[edit]
A medpunkt (health care access point) delivers primary health care to the residents of the village of Veliki Vrag, Russia.

Clinics are often associated with a general medical practice run by one or several general practitioners. Other types of clinics are run by the type of specialist associated with that type: physical therapy clinics by physiotherapists and psychology clinics by clinical psychologists, and so on for each health profession. (This can even hold true for certain services outside the medical field: for example, legal clinics are run by lawyers.)

Some clinics are operated in-house by employers, government organizations, or hospitals, and some clinical services are outsourced to private corporations which specialize in providing health services. In China, for example, owners of such clinics do not have formal medical education. There were 659,596 village clinics in China in 2011.[5]

Health care in India, China, Russia and Africa is provided to those regions' vast rural areas by mobile health clinics or roadside dispensaries, some of which integrate traditional medicine. In India these traditional clinics provide ayurvedic medicine and unani herbal medical practice. In each of these countries, traditional medicine tends to be a hereditary practice.

Function

[edit]
Policlinic in Karl-Marx-Stadt, German Democratic Republic

The function of clinics differs from country to country. For instance, a local general practice run by a single general practitioner provides primary health care and is usually run as a for-profit business by the owner, whereas a government-run specialist clinic may provide subsidized or specialized[dubiousdiscuss] health care.

Some clinics serve as a place for people with injuries or illnesses to be seen by a triage nurse or other health worker. In these clinics, the injury or illness may not be serious enough to require a visit to an emergency room (ER), but the person can be transferred to one if needed.

Treatment at these clinics is often less expensive than it would be at a casualty department. Also, unlike an ER these clinics are often not open on a 24/7/365 basis. They sometimes have access to diagnostic equipment such as X-ray machines, especially if the clinic is part of a larger facility. Doctors at such clinics can often refer patients to specialists if the need arises.[6]

Large outpatient clinics

[edit]
Children Policlinic in Novokosino District of Moscow

Large outpatient clinics vary in size, but can be as large as hospitals.

Function

[edit]

Typical large outpatient clinics house general medical practitioners (GPs) such as doctors and nurses to provide ambulatory care and some acute care services but lack the major surgical and pre- and post-operative care facilities commonly associated with hospitals.

Policlinic in Vilnius-Karoliniškės, Lithuania

Besides GPs, if a clinic is a polyclinic, it can house outpatient departments of some medical specialties, such as gynecology, dermatology, ophthalmology, otolaryngology, neurology, pulmonology, cardiology, and endocrinology. In some university cities, polyclinics contain outpatient departments for the entire teaching hospital in one building.

Internationally

[edit]
Policlinic in Písek, Czech Republic

Large outpatient clinics are a common type of healthcare facility in many countries, including France, Germany (long tradition), Switzerland, and most of the countries of Central and Eastern Europe (often using a mixed Soviet-German model), as well as in former Soviet republics such as Russia and Ukraine;[7] and in many countries across Asia and Africa.[8]

In Europe, especially in the Central and Eastern Europe, bigger outpatient health centers, commonly in cities and towns, are called policlinics (derived from the word polis, not from poly-).

Recent[when?] Russian governments have attempted to replace the policlinic model introduced during Soviet times with a more western model. However, this has failed.[9]

In the Czech Republic, many policlinics were privatized or leasehold and decentralized in the post-communist era: some of them are just lessors and coordinators of a healthcare provided by private doctor's offices in the policlinic building.[10]

India has also set up huge numbers of polyclinics for former defense personnel. The network envisages 426 polyclinics in 343 districts of the country which will benefit about 33 lakh (3.3 million) ex-servicemen residing in remote and far-flung areas.[11]

Policlinics are also the backbone of Cuba's primary care system and have been credited with a role in improving that nation's health indicators.[12]

Mobile clinics

[edit]
Hinduja National Hospital's mobile clinic
A mobile health clinic operated from a truck

Providing health services through mobile clinics provides accessible healthcare services to these remote areas that have yet to make their way in the politicized space. For example, mobile clinics have proved helpful in dealing with new settlement patterns in Costa Rica. Before foreign aid organizations or the state government became involved in healthcare, Costa Rica's people managed their own health maintenance and protection.[13] People relied on various socio-cultural adaptations and remedies to prevent illnesses, such as personal hygiene and settlement patterns.[13] When new settlements that sprang up along the coast became "artificial" communities, and due to lack of traditional home healing practices here, alternative methods such as mobile clinics had to be implemented in these communities for the protection and prevention of diseases.[13]

A study done in rural Namibia revealed the health changes of orphans, vulnerable children and non-vulnerable children (OVC) visiting a mobile clinic where health facilities are far from the remote villages.[14] Over 6 months, information on immunization status, diagnosis of anemia, skin and intestinal disorders, nutrition, dental disorders was collected and showed that visits to mobile clinics improved the overall health of children that visited regularly. It concluded that specified "planning of these programs in areas with similarly identified barriers may help correct the health disparities among Namibian OVC and could be a first step in improving child morbidity and mortality in difficult-to-reach rural areas."[14]

A mobile clinic run from a pickup truck in Yemen

Food supplementation in the context of routine mobile clinic visits also shows to have improved the nutritional status of children, and it needs further exploration as a way to reduce childhood malnutrition in resource-scarce areas. A cross-sectional study focussed on comparing acute and chronic undernutrition rates prior to and after a food-supplementation program as an adjunct to routine health care for children of migrant workers residing in rural communities in the Dominican Republic.[15] Rates of chronic undernutrition decreased from 33% to 18% after the initiation of the food-supplementation program and shows that the community members attending the mobile clinics are not just passively receiving the information but are incorporating it and helping keep their children nourished.[15]

Types

[edit]
Storefront clinic in Manhattan

There are many different types of clinics providing outpatient services. Such clinics may be public (government-funded) or private medical practices.

  • A CLSC are in Quebec; they are a type of free clinic funded by the provincial government; they provide service not covered by Canada's healthcare plan including social workers
  • In the United States, a free clinic provides free or low-cost healthcare for those with little or without insurance.
  • A retail-based clinic is housed in supermarkets and similar retail outlets providing walk-in health care, which may be staffed by nurse practitioners.
  • A general out-patient clinic offers general diagnoses or treatments without an overnight stay.
  • A polyclinic or policlinic provides a range of healthcare services (including diagnostics) without need of an overnight stay
  • A specialist clinic provides advanced diagnostic or treatment services for specific diseases or parts of the body. This type contrasts with general out-patient clinics.

See also

[edit]

References

[edit]
  1. ^ κλινικός in A Greek–English Lexicon. Retrieved 18 September 2016.
  2. ^ clinicus in A Latin Dictionary. Retrieved 18 September 2016.
  3. ^ Partridge, Eric. Origins: A short etymological dictionary of modern English. Book Club Associates, 1966.
  4. ^ Clinic, Webster's Revised Unabridged Dictionary, 1913.
  5. ^ "Statistical Communiqué on the 2011 National Economic and Social Development". stats.gov.cn. National Bureau of Statistics of China. 22 February 2012. Archived from the original on 6 April 2012. Retrieved 5 September 2012.
  6. ^ "Clinic search engine tools to find the right Clinic". 123 clinic. Retrieved 15 December 2016.
  7. ^ NLH – Health Management – Policlinics. Retrieved 3 July 2008.[permanent dead link]
  8. ^ Google
  9. ^ Ershova I, Rider O, Gorelov V (December 2007). "Policlinics in London". Lancet. 370 (9603): 1890–1. doi:10.1016/S0140-6736(07)61793-0. PMID 18068500. S2CID 43512994.
  10. ^ David Rath: Trnitá cesta privatizace českého zdravotnictví, Hospodářské noviny, 10 September 1996
  11. ^ "199 Additional Polyclinics For Ex-Servicemen". The Hindu. Chennai, India. 26 May 2010.
  12. ^ Cuba's primary health care revolution: 30 years on, Bulletin of the World Health Organization
  13. ^ a b c Morgan, Lynn M. (February 1993). Community Participation in Health: The Politics of Primary Care in Costa Rica. doi:10.1017/CBO9780511558092. ISBN 978-0-521-41898-0. Retrieved 8 May 2020. cite book: |website= ignored (help)
  14. ^ a b Aneni, Ehimen; De Beer, Ingrid H.; Hanson, Laura; Rijnen, Bas; Brenan, Alana T.; Feeley, Frank G. (2013). "Mobile primary healthcare services and health outcomes of children in rural Namibia". Rural and Remote Health. 13 (3): 2380. ISSN 1445-6354. PMID 24016257.
  15. ^ a b Parikh, Kavita; Marein-Efron, Gabriela; Huang, Shirley; O'Hare, Geraldine; Finalle, Rodney; Shah, Samir S. (September 2010). "Nutritional Status of Children after a Food-Supplementation Program Integrated with Routine Health Care through Mobile Clinics in Migrant Communities in the Dominican Republic". The American Journal of Tropical Medicine and Hygiene. 83 (3): 559–564. doi:10.4269/ajtmh.2010.09-0485. ISSN 0002-9637. PMC 2929051. PMID 20810820.

Wrinkles on the face and hands are a typical sign of aging

A wrinkle, also known as a rhytid, is a fold, ridge or crease in an otherwise smooth surface, such as on skin or fabric. Skin wrinkles typically appear as a result of ageing processes such as glycation,[1] habitual sleeping positions,[2] loss of body mass, sun damage,[3] or temporarily, as the result of prolonged immersion in water. Age wrinkling in the skin is promoted by habitual facial expressions, aging, sun damage, smoking, poor hydration, and various other factors.[4] In humans, it can also be prevented to some degree by avoiding excessive solar exposure and through diet (in particular through consumption of carotenoids, tocopherols and flavonoids, vitamins (A, C, D and E), essential omega-3-fatty acids, certain proteins and lactobacilli).[5]

Skin

[edit]

Causes for aging wrinkles

[edit]
A woman of European origin with facial wrinkles

Development of facial wrinkles is a kind of fibrosis of the skin. Misrepair-accumulation aging theory suggests that wrinkles develop from incorrect repairs of injured elastic fibers and collagen fibers.[6][7][8] Repeated extensions and compressions of the skin cause repeated injuries of extracellular fibers in derma. During the repairing process, some of the broken elastic fibers and collagen fibers are not regenerated and restored but replaced by altered fibers. When an elastic fiber is broken in an extended state, it may be replaced by a "long" collagen fiber. Accumulation of "long" collagen fibers makes part of the skin looser and stiffer, and as a consequence, a big fold of skin appears. When a "long" collagen is broken in a compressed state, it may be replaced by a "short" collagen fiber. The "shorter" collagen fibers will restrict the extension of "longer" fibers, and make the “long" fibers in a folding state permanently. A small fold, namely a permanent wrinkle, then appears.

Sleep wrinkles

[edit]

Sleep wrinkles are created and reinforced when the face is compressed against a pillow or bed surface in side or stomach sleeping positions during sleep.[9] They appear in predictable locations due to the underlying superficial musculoaponeurotic system (SMAS), and are usually distinct from wrinkles of facial expression.[10] As with wrinkles of facial expression, sleep wrinkles can deepen and become permanent over time, unless the habitual sleeping positions which cause the wrinkles are altered.[11]

Water-immersion wrinkling

[edit]
A wrinkled finger after a warm bath

The wrinkles that occur in skin over prolonged exposure to water are sometimes referred to as pruney fingers or water aging. This is a temporary skin condition where the skin on the palms of the hand or feet becomes wrinkly. This wrinkling response may have imparted an evolutionary benefit by providing improved traction in wet conditions,[12] and a better grasp of wet objects.[13] These results were called into question by a 2014 study that failed to reproduce any improvement of handling wet objects with wrinkled fingertips.[14] However, a 2020 study of gripping efficiency found that wrinkles decreased the force required to grip wet objects by 20%, supporting the traction hypothesis.[15]

Prior to a 1935 study, the common explanation was based on water absorption in the keratin-laden epithelial skin when immersed in water,[16] causing the skin to expand and resulting in a larger surface area, forcing it to wrinkle. Usually the tips of the fingers and toes are the first to wrinkle because of a thicker layer of keratin and an absence of hairs which secrete the protective oil called sebum.

Adult sole showing water immersion wrinkling

In the 1935 study, however, Lewis and Pickering were studying patients with palsy of the median nerve when they discovered that skin wrinkling did not occur in the areas of the patients' skin normally innervated by the damaged nerve. This suggested that the nervous system plays an essential role in wrinkling, so the phenomenon could not be entirely explained simply by water absorption. Recent research shows that wrinkling is related to vasoconstriction.[17][18] Water probably initiates the wrinkling process by altering the balance of electrolytes in the skin as it diffuses into the hands and soles via their many sweat ducts. This could alter the stability of the membranes of the many neurons that synapse on the many blood vessels underneath skin, causing them to fire more rapidly. Increased neuronal firing causes blood vessels to constrict, decreasing the amount of fluid underneath the skin. This decrease in fluid would cause a decrease in tension, causing the skin to become wrinkly.[19]

This insight resulted in bedside tests for nerve damage and vasoconstriction. Wrinkling is often scored with immersion of the hands for 30 minutes in water or EMLA cream with measurements steps of 5 minutes, and counting the number of visible wrinkles in time. Not all healthy persons have finger wrinkling after immersion, so it would be safe to say that sympathetic function is preserved if finger wrinkling after immersion in water is observed, but if the fingers emerge smooth it cannot be assumed that there is a lesion to the autonomic supply or to the peripheral nerves of the hand.[20]

Other animals with wrinkles

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Examples of wrinkles can be found in various animal species that grow loose, excess skin, particularly when they are young. Several breeds of dog, such as the Pug and the Shar Pei, have been bred to exaggerate this trait. In dogs bred for fighting, this is the result of selection for loose skin, which confers a protective advantage.[21]

Techniques for reducing the appearance of aging wrinkles

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A man receiving a botox injection

Current evidence suggests that tretinoin decreases cohesiveness of follicular epithelial cells, although the exact mode of action is unknown. Additionally, tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells.[22] Tretinoin is better known by the brand name Retin-A.

Topical glycosaminoglycans supplements can help to provide temporary restoration of enzyme balance to slow or prevent matrix breakdown and consequent onset of wrinkle formation. Glycosaminoglycans (GAGs) are produced by the body to maintain structural integrity in tissues and to maintain fluid balance. Hyaluronic acid is a type of GAG that promotes collagen synthesis, repair, and hydration. GAGs serve as a natural moisturizer and lubricant between epidermal cells to inhibit the production of matrix metalloproteinases (MMPs).

Dermal fillers are injectable products frequently used to correct wrinkles, and other depressions in the skin. They are often a kind of soft tissue designed to enable injection into the skin for purposes of improving the appearance. The most common products are based on hyaluronic acid and calcium hydroxylapatite.

Botulinum toxin is a neurotoxin protein produced by the bacterium Clostridium botulinum. Botox is a specific form of botulinum toxin manufactured by Allergan for both therapeutic and cosmetic use. Besides its cosmetic application, Botox is used in the treatment of other conditions including migraine headache and cervical dystonia (spasmodic torticollis) (a neuromuscular disorder involving the head and neck).[23]

Dysport, manufactured by Ipsen, received FDA approval and is now used to treat cervical dystonia as well as glabellar lines in adults. In 2010, another form of botulinum toxin, one free of complexing proteins, became available to Americans. Xeomin received FDA approval for medical indications in 2010 and cosmetic indications in 2011.

Botulinum toxin treats wrinkles by immobilizing the muscles which cause wrinkles. It is not appropriate for the treatment of all wrinkles; it is indicated for the treatment of glabellar lines (between the eyebrows) in adults. Any other usage is not approved by the FDA and is considered off-label use.

Laser resurfacing is FDA-cleared skin resurfacing procedure in which lasers are used to improve the condition of the skin.[citation needed] Two types of lasers are used to reduce the appearance of fine lines and wrinkles on the face; laser ablation, which removes thin layers of skin, and nonablative lasers that stimulate collagen production. Nonablative lasers are less effective than ablative ones but they are less invasive and recovery time is short. After the procedure people experience temporary redness, itching and swelling.

See also

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References

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  1. ^ Danby, FW (Jul–Aug 2010). "Nutrition and aging skin: sugar and glycation". Clin Dermatol. 4. 28 (4): 409–411. doi:10.1016/j.clindermatol.2010.03.018. PMID 20620757.
  2. ^ American Academy of Dermatology. "Causes of Aging". AgingSkinNet. American Academy of Dermatology. Retrieved 5 March 2013.
  3. ^ Cosmetic Procedures for Wrinkles
  4. ^ Anderson, Laurence. 2006. Looking Good, the Australian guide to skin care, cosmetic medicine and cosmetic surgery. AMPCo. Sydney. ISBN 0-85557-044-X.
  5. ^ Schagen, S. K.; Zampeli, V. A.; Makrantonaki, E.; Zouboulis, C. C. (2012). "Discovering the link between nutrition and skin aging". Dermato-Endocrinology. 4 (3): 298–307. doi:10.4161/derm.22876. PMC 3583891. PMID 23467449.
  6. ^ Wang, Jicun; Michelitsch, Thomas; Wunderlin, Arne; Mahadeva, Ravi (2009). "Aging as a consequence of Misrepair—a novel theory of aging". arXiv:0904.0575 [q-bio.TO].
  7. ^ Wang-Michelitsch, Jicun; Michelitsch, Thomas (2015). "Aging as a process of accumulation of Misrepairs". arXiv:1503.07163 [q-bio.TO].
  8. ^ Wang-Michelitsch, Jicun; Michelitsch, Thomas (2015). "Tissue fibrosis: a principal evidence for the central role of Misrepairs in aging". arXiv:1505.01376 [q-bio.TO].
  9. ^ Sarifakioglu, Nedim; Terzioglu, A.; Ates, L.; Aslan, G. (2004). "A New Phenomenon: 'Sleep Lines' on the Face". Scan J Plast Reconstr Surg Hand Surg. 38 (4): 244–247. doi:10.1080/02844310410027257. PMID 15370809. S2CID 25307487.
  10. ^ Fulton, James E.; Gaminchi, F. (1999). "Sleep Lines". Dermatol Surg. 25 (1): 59–62. doi:10.1046/j.1524-4725.1999.08073.x. PMID 9935097.
  11. ^ Sarifakioglu, Nedim; Terzioglu, A.; Ates, L.; Aslan, G. (2004). "A New Phenomenon: 'Sleep Lines' on the Face". Scan J Plast Reconstr Surg Hand Surg. 38 (4): 244–247 [246]. doi:10.1080/02844310410027257. PMID 15370809. S2CID 25307487.
  12. ^ Mark Changizi; Romann Weber; Ritesh Kotecha; Joseph Palazzo (2011). "Are Wet-Induced Wrinkled Fingers Primate Rain Treads?". Brain, Behavior and Evolution. 77 (4): 286–90. doi:10.1159/000328223. PMID 21701145.
  13. ^ Kareklas, Kyriacos; Nettle, Daniel; Smulders, Tom V (January 9, 2013). "Water-induced finger wrinkles improve handling of wet objects". Biol. Lett. 9 (2): 20120999. doi:10.1098/rsbl.2012.0999. PMC 3639753. PMID 23302867.
  14. ^ Haseleu, Julia; Omerbašić, Damir; Frenzel, Henning; Gross, Manfred; Lewin, Gary R. (2014). Goldreich, Daniel (ed.). "Water-Induced Finger Wrinkles Do Not Affect Touch Acuity or Dexterity in Handling Wet Objects". PLOS ONE. 9 (1): e84949. Bibcode:2014PLoSO...984949H. doi:10.1371/journal.pone.0084949. PMC 3885627. PMID 24416318.
  15. ^ Davis, N. (8 November 2020). "Water-immersion finger-wrinkling improves grip efficiency in handling wet objects". bioRxiv 10.1101/2020.11.07.372631.
  16. ^ "Dr Karl's Homework – Skin Wrinkles in Water (26/1/2000)". Abc.net.au. 2000-01-26. Retrieved 2019-04-30.
  17. ^ Einar P.V. Wilder-Smith; Adeline Chow (2003). "Water-immersion wrinkeling is due to vasoconstriction". Muscle & Nerve. 27 (3): 307–311. doi:10.1002/mus.10323. PMID 12635117. S2CID 45193684.
  18. ^ Einar P. V. Wilder-Smith (2004). "Water immersion wrinkling". Clinical Autonomic Research. 14 (2): 125–131. doi:10.1007/s10286-004-0172-4. PMID 15095056. S2CID 44938772.
  19. ^ H. Zhai, K.P. Whilem H. L. Maibach (2007). Dermatotoxicology. pp. 280–281.
  20. ^ G Alvarez, J Eurolo; P Canales (1980). "Finger wrinkling after immersion in water". British Medical Journal. 281 (6240): 586–587. doi:10.1136/bmj.281.6240.586-a. PMC 1713922. PMID 7427379.
  21. ^ The Dog Encyclopedia: The Definitive Visual Guide. Penguin. 15 August 2023. p. 84. ISBN 978-0-7440-8513-6.
  22. ^ Stefanaki C, Stratigos A, Katsambas A (June 2005). "Topical retinoids in the treatment of photoaging". J Cosmet Dermatol. 4 (2): 130–4. doi:10.1111/j.1473-2165.2005.40215.x. PMID 17166212. S2CID 44702740.
  23. ^ Brin MF, Lew MF, Adler CH, Comella CL, Factor SA, Jankovic J, O'Brien C, Murray JJ, Wallace JD, Willmer-Hulme A, Koller M (1999). "Safety and efficacy of NeuroBloc (botulinum toxin type B) in type A-resistant cervical dystonia". Neurology. 53 (7): 1431–8. doi:10.1212/WNL.53.7.1431. PMID 10534247.
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Frequently Asked Questions

You'll want a practitioner with specialized training in dermatology or plastic surgery and significant experience in administering Botox and fillers. Ensure they're certified and have a track record of safe and effective treatments.

You might experience bruising, swelling, or redness at injection sites. Rarely, you could face infection, allergic reactions, or asymmetry. With Botox, there's a slight risk of drooping eyelids or muscle weakness. Always consult a professional.

You're exploring the less talked about, yet vital, side of cosmetic treatments: patient safety and awareness. It's key to understand the risks and side effects of procedures like botox and fillers for informed decisions.